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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-4-18
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pubmed:abstractText |
This study was designed to assess the validity of the percent of volume expired at tidal peak flow (dV/Vt) as an indicator of bronchial obstruction in school-age children. We analyzed 126 dV/Vt ratios and compared them with spirometric and plethysmographic results measured in 24 healthy (14 males) and 60 asthmatic (41 males) children; 42 of them underwent measurements before and after bronchial challenge with histamine. The two groups differed in resistance, forced expiratory volume in 1 sec (FEV1), and forced expiratory flows, as percents of predicted (FEV1: 94.6 +/- 2.4% in controls vs 86.7 +/- 1.6% in asthmatics; P less than 0.001). They did not differ in peak expiratory flow (PEF), forced vital capacity, functional residual capacity, measured by body plethysmography, and in dV/Vt. The dV/Vt was found to correlate with FEV1 (r = 0.58, P less than 0.001), PEF (r = 0.57, P less than 0.001), and other lung function parameters. Forty-two of the asthmatic children performed a bronchoprovocation histamine test. The fall of dV/Vt after histamine was significantly correlated (r = 0.61, P less than 0.001) with the variation in FEV1 and other lung function parameters. We conclude that dV/Vt is a good indicator of bronchial obstruction, as useful in school-age children as in adults and infants, with no need for the subject's cooperation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
8755-6863
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2003048-Adolescent,
pubmed-meshheading:2003048-Airway Resistance,
pubmed-meshheading:2003048-Asthma,
pubmed-meshheading:2003048-Bronchial Provocation Tests,
pubmed-meshheading:2003048-Child,
pubmed-meshheading:2003048-Child, Preschool,
pubmed-meshheading:2003048-Female,
pubmed-meshheading:2003048-Forced Expiratory Flow Rates,
pubmed-meshheading:2003048-Functional Residual Capacity,
pubmed-meshheading:2003048-Histamine,
pubmed-meshheading:2003048-Humans,
pubmed-meshheading:2003048-Male,
pubmed-meshheading:2003048-Peak Expiratory Flow Rate,
pubmed-meshheading:2003048-Plethysmography,
pubmed-meshheading:2003048-Respiratory Mechanics,
pubmed-meshheading:2003048-Spirometry,
pubmed-meshheading:2003048-Vital Capacity
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pubmed:year |
1991
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pubmed:articleTitle |
Analysis of expiratory pattern for monitoring bronchial obstruction in school-age children.
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pubmed:affiliation |
4th Department of Pediatric Clinics, University of Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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