Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-4-18
pubmed:abstractText
Toxic vapor abuse during pregnancy was found to be associated with increased maternal and fetal morbidity. Toluene-induced renal tubular acidosis occurred in over half of these women and was clustered among long-duration abusers. The renal acidosis placed the mother at risk for hypokalemia, with associated cardiac dysrhythmias and rhabdomyolysis. Beta-mimetics and intravenous fluid for preterm labor therapy potentially exacerbated the electrolyte abnormalities. Among 21 newborns exposed to toluene in utero, preterm delivery, perinatal death, and growth retardation were significantly increased. Delivery during uncorrected maternal acidosis further compromised these infants. As children, growth retardation and developmental delay were common findings. Recognition of the unique obstetric and medical characteristics of the toluene-abusing woman is needed if complications are to be averted and perinatal outcomes improved.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0029-7844
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
504-9
pubmed:dateRevised
2009-10-26
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Toluene abuse during pregnancy: obstetric complications and perinatal outcomes.
pubmed:affiliation
Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center, Denver General Hospital.
pubmed:publicationType
Journal Article