|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2009-12-23
|
|
pubmed:abstractText |
Rat lung allograft rejection is mediated by collagen type V (col(V)) specific T-helper-cell 17 (Th17) cells. Adoptive transfer of these cells is sufficient to induce rejection pathology in isografts, whereas tolerance to col(V) suppresses allograft rejection. Therefore, we tested whether regulatory T cells from tolerant rats could suppress the Th17-mediated rejection in the syngeneic model of lung transplantation.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1534-6080
|
|
pubmed:author |
pubmed-author:BrandDavid DDD,
pubmed-author:BraunRuedi KRK,
pubmed-author:BurlinghamWilliam JWJ,
pubmed-author:FainSean BSB,
pubmed-author:Jankowska-GanEwaE,
pubmed-author:LoveRobert BRB,
pubmed-author:Molitor-DartMelanieM,
pubmed-author:SeroogyChristine MCM,
pubmed-author:TorrealbaJoseJ,
pubmed-author:WigfieldChristopherC,
pubmed-author:WilkesDavid SDS,
pubmed-author:XiangZhuzaiZ
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
27
|
|
pubmed:volume |
88
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1341-8
|
|
pubmed:dateRevised |
2011-4-26
|
|
pubmed:meshHeading |
pubmed-meshheading:20029330-Acute Disease,
pubmed-meshheading:20029330-Animals,
pubmed-meshheading:20029330-Collagen Type V,
pubmed-meshheading:20029330-Disease Models, Animal,
pubmed-meshheading:20029330-Graft Rejection,
pubmed-meshheading:20029330-Immunity, Cellular,
pubmed-meshheading:20029330-Immunohistochemistry,
pubmed-meshheading:20029330-Interleukin-17,
pubmed-meshheading:20029330-Lung Transplantation,
pubmed-meshheading:20029330-Positron-Emission Tomography,
pubmed-meshheading:20029330-Rats,
pubmed-meshheading:20029330-Rats, Inbred F344,
pubmed-meshheading:20029330-Rats, Inbred WKY,
pubmed-meshheading:20029330-T-Lymphocyte Subsets,
pubmed-meshheading:20029330-Transplantation, Homologous
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Transfer of tolerance to collagen type V suppresses T-helper-cell-17 lymphocyte-mediated acute lung transplant rejection.
|
|
pubmed:affiliation |
Department of Thoracic and Cardiovascular Surgery, Loyola University, Maywood, IL 60153, USA. rubraun@lumc.edu
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
|
