Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-1-29
pubmed:abstractText
We present CSDeconv, a computational method that determines locations of transcription factor binding from ChIP-seq data. CSDeconv differs from prior methods in that it uses a blind deconvolution approach that allows closely-spaced binding sites to be called accurately. We apply CSDeconv to novel ChIP-seq data for DosR binding in Mycobacterium tuberculosis and to existing data for GABP in humans and show that it can discriminate binding sites separated by as few as 40 bp.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-10970762, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-11416222, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-11891299, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-12446625, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-12694625, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-12953091, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-12953092, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-14762058, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-16227431, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-16845028, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-16895995, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-17277770, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-17540862, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-17558387, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-17603471, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-17664943, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-17727723, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-18599518, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-18684996, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-18725927, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-18784119, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-18798982, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-18978777, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-19029915, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-19122651, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-19160518, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-19553195, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-8383622, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-9520501, http://linkedlifedata.com/resource/pubmed/commentcorrection/20028542-9689123
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1465-6914
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R142
pubmed:dateRevised
2010-9-28
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
A blind deconvolution approach to high-resolution mapping of transcription factor binding sites from ChIP-seq data.
pubmed:affiliation
Phenomics and Bioinformatics Research Centre, School of Mathematics and Statistics, and Australian Centre for Plant Functional Genomics, University of South Australia, Mawson Lakes Boulevard, Mawson Lakes, SA 5095, Australia. desmond.lun@unisa.edu.au
pubmed:publicationType
Journal Article