20027199

Source:http://linkedlifedata.com/resource/pubmed/id/20027199

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0231337, umls-concept:C1332733, umls-concept:C1707719
pubmed:issue	1
pubmed:dateCreated	2009-12-22
pubmed:abstractText	Cdk2 has been shown to have an unanticipated role in suppressing Myc-induced senescence. This has implications for how c-Myc overcomes failsafe mechanisms to induce tumorigenesis and suggests that the inhibition of Cdk2 may have therapeutic efficacy in the treatment of cancer.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100890575
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase 2
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1476-4679
pubmed:author	pubmed-author:FelsherDean WDW, pubmed-author:van RiggelenJanJ
pubmed:issnType	Electronic
pubmed:volume	12
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	7-9
pubmed:meshHeading	pubmed-meshheading:20027199-Animals, pubmed-meshheading:20027199-Cell Aging, pubmed-meshheading:20027199-Cyclin-Dependent Kinase 2, pubmed-meshheading:20027199-Genes, myc, pubmed-meshheading:20027199-Humans, pubmed-meshheading:20027199-Neoplasms
pubmed:year	2010
pubmed:articleTitle	Myc and a Cdk2 senescence switch.
pubmed:publicationType	News