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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
1991-4-17
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pubmed:abstractText |
The effect of insulin-like growth factor I (IGF-I) on renal blood flow was measured in the anaesthetized rat using an electromagnetic flow probe. Renal vasodilation induced by IGF-I (50 micrograms/kg) was completely inhibited by NG-nitro-l-arginine methyl ester (50 mg/kg), an inhibitor of nitric oxide biosynthesis, but only partially reduced by indomethacin (10 mg/kg). The involvement of nitric oxide synthesis in the renal actions of IGF-I is proposed.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
|
|
pubmed:issn |
0085-2538
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
39
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
333-5
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2002647-Animals,
pubmed-meshheading:2002647-Arginine,
pubmed-meshheading:2002647-Indomethacin,
pubmed-meshheading:2002647-Insulin-Like Growth Factor I,
pubmed-meshheading:2002647-Kidney,
pubmed-meshheading:2002647-Male,
pubmed-meshheading:2002647-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:2002647-Nitric Oxide,
pubmed-meshheading:2002647-Rats,
pubmed-meshheading:2002647-Rats, Inbred Strains,
pubmed-meshheading:2002647-Renal Circulation,
pubmed-meshheading:2002647-Vasodilation
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pubmed:year |
1991
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|
pubmed:articleTitle |
Nitric oxide synthesis inhibitor prevents vasodilation by insulin-like growth factor I.
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pubmed:affiliation |
Department of Medicine and Pharmacology, Royal Hallamshire Hospital, Sheffield, England, United Kingdom.
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pubmed:publicationType |
Journal Article
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