Linked Life Data

20025851

Source:http://linkedlifedata.com/resource/pubmed/id/20025851

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-1-27
pubmed:abstractText
The effects of human tobacco smoking and nicotine on pain-related brain activities were investigated. EEG responses evoked by a painful laser beam (laser evoked potentials; LEPs), and the plasma nicotine concentration (PNC) were measured. There were two sessions, one after smoking (Smoking session), and the other in no smoking (Control session). Subjective ratings of pain perception were also measured using the visual analog scale (VAS). Two major components, N2 and P2 of LEPs, were recorded. The amplitude of P2 was significantly smaller in the Smoking session than in the Control session. A significant negative correlation was found between PNC and the amplitude of N2 as well as P2. The results were consistent with the hypothesis that smoking and/or nicotine have an antinociceptive effect, which supports most non-human studies and some human studies. Smoking of a single tobacco cigarette did not show a subjectively perceivable extent of reduction in the intensity of evoked pain.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1872-6240
pubmed:author
pubmed:copyrightInfo
Copyright 2009 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
8
pubmed:volume
1313
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-91
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The effect of smoking on pain-related evoked potentials.
pubmed:affiliation
Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji-cho, Okazaki 444-8585, Japan. miyazaki@nips.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural