Linked Life Data

20025236

Source:http://linkedlifedata.com/resource/pubmed/id/20025236

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-1-22
pubmed:abstractText
Six new triterpene dilactones with a rare rearranged pentacyclic skeleton, longipedlactones K-P (1-6), and seven known analogues (7-13) were isolated from the stems of Kadsura ananosma. Compound 1 was found to possess a unique peroxide bridge between C-1 and C-9 in rings A and B. The structures of these new compounds were established on the basis of spectroscopic data analysis, especially of their 2D NMR spectra. In the evaluation of the in vitro cytotoxicity of these compounds against a small panel of human cancer cell lines, compounds 3, 7, 9, and 13 were found to be the most potent against HL-60 acute leukemia cell.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1520-6025
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
12-6
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Cytotoxic triterpene dilactones from the stems of Kadsura ananosma.
pubmed:affiliation
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't