20023039

Source:http://linkedlifedata.com/resource/pubmed/id/20023039

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0024501, umls-concept:C0040649, umls-concept:C0392673, umls-concept:C0428876, umls-concept:C0441655, umls-concept:C0521451, umls-concept:C0721534
pubmed:issue	1
pubmed:dateCreated	2009-12-21
pubmed:abstractText	The transcription factor MEF2 is a downstream target for several hypertrophic signalling pathways in the heart, suggesting that MEF2 may act as a valuable therapeutic target in the treatment of heart failure.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100887595
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/8-hydroxy-2'-deoxyguanosine, http://linkedlifedata.com/resource/pubmed/chemical/Cre recombinase, http://linkedlifedata.com/resource/pubmed/chemical/Deoxyguanosine, http://linkedlifedata.com/resource/pubmed/chemical/Integrases, http://linkedlifedata.com/resource/pubmed/chemical/Mef2a protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Myogenic Regulatory Factors, http://linkedlifedata.com/resource/pubmed/chemical/NADH Dehydrogenase, http://linkedlifedata.com/resource/pubmed/chemical/NADH dehydrogenase subunit 6, mouse
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1879-0844
pubmed:author	pubmed-author:BergmannMartin WMW, pubmed-author:De WindtLeon JLJ, pubmed-author:SluiterWimW, pubmed-author:el AzzouziHamidH, pubmed-author:van OortRalph JRJ, pubmed-author:van der NagelRoelR
pubmed:issnType	Electronic
pubmed:volume	12
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4-12
pubmed:dateRevised	2011-6-8
pubmed:meshHeading	pubmed-meshheading:20023039-Animals, pubmed-meshheading:20023039-Apoptosis, pubmed-meshheading:20023039-Cardiomegaly, pubmed-meshheading:20023039-Deoxyguanosine, pubmed-meshheading:20023039-Disease Models, Animal, pubmed-meshheading:20023039-Echocardiography, pubmed-meshheading:20023039-Gene Expression, pubmed-meshheading:20023039-Heart Failure, pubmed-meshheading:20023039-Integrases, pubmed-meshheading:20023039-Mice, pubmed-meshheading:20023039-Mice, Transgenic, pubmed-meshheading:20023039-Mitochondria, Heart, pubmed-meshheading:20023039-Myocytes, Cardiac, pubmed-meshheading:20023039-Myogenic Regulatory Factors, pubmed-meshheading:20023039-NADH Dehydrogenase, pubmed-meshheading:20023039-Transcription, Genetic, pubmed-meshheading:20023039-Treatment Outcome, pubmed-meshheading:20023039-Ventricular Remodeling
pubmed:year	2010
pubmed:articleTitle	MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload.
pubmed:affiliation	Department of Cardiology, Faculty of Health, Medicine and Life Sciences, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't