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rdf:type |
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lifeskim:mentions |
umls-concept:C0011570,
umls-concept:C0013030,
umls-concept:C0013806,
umls-concept:C0030705,
umls-concept:C0032743,
umls-concept:C0205094,
umls-concept:C0526599,
umls-concept:C0547047,
umls-concept:C0597358,
umls-concept:C0599278,
umls-concept:C0681867
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pubmed:issue |
6
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pubmed:dateCreated |
2010-6-24
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pubmed:abstractText |
Electroconvulsive therapy (ECT) has been confirmed as one of the most effective treatments in drug-resistant major depression. However, the mechanism of ECT is still poorly understood. Although several lines of studies have focused on its effect on dopamine neurotransmission, the effects of ECT on dopamine D(2) receptors in a living human brain have not been investigated. Using positron emission tomography (PET) scans with the radioligand [(11)C]FLB 457, we aimed to evaluate the effect of ECT on extrastriatal D(2) receptor binding in medicated patients with major depressive disorder (MDD).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1555-2101
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pubmed:author |
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pubmed:copyrightInfo |
2010 Physicians Postgraduate Press, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
793-9
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pubmed:dateRevised |
2011-1-24
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pubmed:meshHeading |
pubmed-meshheading:20021995-Adult,
pubmed-meshheading:20021995-Carbon Radioisotopes,
pubmed-meshheading:20021995-Depressive Disorder, Major,
pubmed-meshheading:20021995-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:20021995-Dopamine Antagonists,
pubmed-meshheading:20021995-Electroconvulsive Therapy,
pubmed-meshheading:20021995-Female,
pubmed-meshheading:20021995-Functional Laterality,
pubmed-meshheading:20021995-Gyrus Cinguli,
pubmed-meshheading:20021995-Humans,
pubmed-meshheading:20021995-Male,
pubmed-meshheading:20021995-Middle Aged,
pubmed-meshheading:20021995-Positron-Emission Tomography,
pubmed-meshheading:20021995-Pyrrolidines,
pubmed-meshheading:20021995-Radioligand Assay,
pubmed-meshheading:20021995-Receptors, Dopamine D2,
pubmed-meshheading:20021995-Salicylamides,
pubmed-meshheading:20021995-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Electroconvulsive therapy decreases dopamine D?receptor binding in the anterior cingulate in patients with depression: a controlled study using positron emission tomography with radioligand [¹¹C]FLB 457.
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pubmed:affiliation |
Department of Neuropsychiatry, Nippon Medical School, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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