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rdf:type |
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lifeskim:mentions |
umls-concept:C0003261,
umls-concept:C0026809,
umls-concept:C0057256,
umls-concept:C0079189,
umls-concept:C0085478,
umls-concept:C0243040,
umls-concept:C0599946,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2349975,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
2009-12-21
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pubmed:abstractText |
Our aim is to assess the ability of human neutrophil peptide alpha-defensins (HNPs) and human beta-defensins (HBDs) to attenuate proinflammatory cytokine responses and enhance antibody responses to recombinant hemagglutinin B (rHagB) or recombinant fimbrillin A (rFimA) from Porphyromonas gingivalis 381 in mice.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adhesins, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Fimbriae Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/HagB protein, Porphyromonas...,
http://linkedlifedata.com/resource/pubmed/chemical/Lectins,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Defensins,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Defensins,
http://linkedlifedata.com/resource/pubmed/chemical/fimbrillin
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1746-0921
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-25
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pubmed:dateRevised |
2011-2-18
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pubmed:meshHeading |
pubmed-meshheading:20020833-Adhesins, Bacterial,
pubmed-meshheading:20020833-Animals,
pubmed-meshheading:20020833-Antibodies, Bacterial,
pubmed-meshheading:20020833-Bacteroidaceae Infections,
pubmed-meshheading:20020833-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:20020833-Cytokines,
pubmed-meshheading:20020833-Female,
pubmed-meshheading:20020833-Fimbriae Proteins,
pubmed-meshheading:20020833-Humans,
pubmed-meshheading:20020833-Lectins,
pubmed-meshheading:20020833-Mice,
pubmed-meshheading:20020833-Mice, Inbred C57BL,
pubmed-meshheading:20020833-Nasal Cavity,
pubmed-meshheading:20020833-Porphyromonas gingivalis,
pubmed-meshheading:20020833-Saliva,
pubmed-meshheading:20020833-Serum,
pubmed-meshheading:20020833-alpha-Defensins,
pubmed-meshheading:20020833-beta-Defensins
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pubmed:year |
2010
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pubmed:articleTitle |
Defensins attenuate cytokine responses yet enhance antibody responses to Porphyromonas gingivalis adhesins in mice.
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pubmed:affiliation |
Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA. karl-kohlgraf@uiowa.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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