|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2010-2-15
|
|
pubmed:abstractText |
The variability in warfarin dose requirement is attributable to genetic and environmental factors. Acenocoumarol (AC) and phenprocoumon (PC) are coumarin derivates widely prescribed in European countries for the prevention and treatment of thromboembolic events. The aim of our study was to investigate the contribution of genes involved in the vitamin K cycle to AC and PC maintenance doses.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acenocoumarol,
http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases,
http://linkedlifedata.com/resource/pubmed/chemical/CALU protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CYP2C9 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Carbon-Carbon Ligases,
http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases,
http://linkedlifedata.com/resource/pubmed/chemical/Phenprocoumon,
http://linkedlifedata.com/resource/pubmed/chemical/glutamyl carboxylase,
http://linkedlifedata.com/resource/pubmed/chemical/vitamin K epoxidase
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1432-1041
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
66
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
253-60
|
|
pubmed:meshHeading |
pubmed-meshheading:20020283-Acenocoumarol,
pubmed-meshheading:20020283-Administration, Oral,
pubmed-meshheading:20020283-Adolescent,
pubmed-meshheading:20020283-Adult,
pubmed-meshheading:20020283-Aged,
pubmed-meshheading:20020283-Aged, 80 and over,
pubmed-meshheading:20020283-Anticoagulants,
pubmed-meshheading:20020283-Apolipoproteins E,
pubmed-meshheading:20020283-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:20020283-Calcium-Binding Proteins,
pubmed-meshheading:20020283-Carbon-Carbon Ligases,
pubmed-meshheading:20020283-Chi-Square Distribution,
pubmed-meshheading:20020283-Female,
pubmed-meshheading:20020283-Gene Frequency,
pubmed-meshheading:20020283-Genotype,
pubmed-meshheading:20020283-Hemorrhage,
pubmed-meshheading:20020283-Heterozygote,
pubmed-meshheading:20020283-Homozygote,
pubmed-meshheading:20020283-Humans,
pubmed-meshheading:20020283-Male,
pubmed-meshheading:20020283-Middle Aged,
pubmed-meshheading:20020283-Mixed Function Oxygenases,
pubmed-meshheading:20020283-Phenotype,
pubmed-meshheading:20020283-Phenprocoumon,
pubmed-meshheading:20020283-Polymorphism, Single Nucleotide,
pubmed-meshheading:20020283-Regression Analysis,
pubmed-meshheading:20020283-Young Adult
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Genetic determinants of acenocoumarol and phenprocoumon maintenance dose requirements.
|
|
pubmed:affiliation |
Department of Laboratory Medicine, Paracelsus Medical University and Universitätsklinikum Salzburg, Austria.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
