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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-12-17
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pubmed:abstractText |
We have previously shown that the enterotoxin SigA which resides on the she pathogenicity island (PAI) of S. flexneri 2a is an autonomously secreted serine protease capable of degrading casein. We have also demonstrated that SigA is cytopathic for HEp-2 cells and plays a role in the intestinal fluid accumulation associated with S. flexneri infections.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-10531204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-10768931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-10992503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-11162180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-11179284,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-11553531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-11553574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-12753188,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-15155671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-15385451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-15499528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-15681156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-3074159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-3310456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-7476198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-8993318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20011051-9778731
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e8223
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pubmed:dateRevised |
2010-9-27
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pubmed:meshHeading |
pubmed-meshheading:20011051-Antibody Formation,
pubmed-meshheading:20011051-Bacterial Proteins,
pubmed-meshheading:20011051-Carrier Proteins,
pubmed-meshheading:20011051-Cell Line,
pubmed-meshheading:20011051-Enterotoxins,
pubmed-meshheading:20011051-Epithelial Cells,
pubmed-meshheading:20011051-Humans,
pubmed-meshheading:20011051-Microfilament Proteins,
pubmed-meshheading:20011051-Protein Binding,
pubmed-meshheading:20011051-Protein Transport,
pubmed-meshheading:20011051-Shigella flexneri
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pubmed:year |
2009
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pubmed:articleTitle |
The immunogenic SigA enterotoxin of Shigella flexneri 2a binds to HEp-2 cells and induces fodrin redistribution in intoxicated epithelial cells.
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pubmed:affiliation |
Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Australia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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