|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007131,
umls-concept:C0008976,
umls-concept:C0019638,
umls-concept:C0034656,
umls-concept:C0035820,
umls-concept:C0040808,
umls-concept:C0205179,
umls-concept:C0205214,
umls-concept:C0684224,
umls-concept:C0936012,
umls-concept:C1514923,
umls-concept:C1879313
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|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2009-12-16
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|
pubmed:abstractText |
Although histology has not consistently been associated with treatment outcome in advanced non-small cell lung cancer, a recent phase III trial comparing pemetrexed plus cisplatin and gemcitabine plus cisplatin (GC) demonstrated better efficacy for pemetrexed plus cisplatin in nonsquamous (adenocarcinoma and large cell carcinoma) carcinoma than in squamous cell carcinoma. Herein, retrospective analysis is used to explore the potential predictive and prognostic role of non-small cell lung cancer histology in patients treated with three first-line, platinum-based regimens.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1556-1380
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
4
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1568-71
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|
pubmed:meshHeading |
pubmed-meshheading:20009911-Adenocarcinoma,
pubmed-meshheading:20009911-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20009911-Carboplatin,
pubmed-meshheading:20009911-Carcinoma, Large Cell,
pubmed-meshheading:20009911-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20009911-Carcinoma, Squamous Cell,
pubmed-meshheading:20009911-Cisplatin,
pubmed-meshheading:20009911-Deoxycytidine,
pubmed-meshheading:20009911-Female,
pubmed-meshheading:20009911-Follow-Up Studies,
pubmed-meshheading:20009911-Humans,
pubmed-meshheading:20009911-Lung Neoplasms,
pubmed-meshheading:20009911-Male,
pubmed-meshheading:20009911-Paclitaxel,
pubmed-meshheading:20009911-Prognosis,
pubmed-meshheading:20009911-Retrospective Studies,
pubmed-meshheading:20009911-Survival Rate,
pubmed-meshheading:20009911-Time Factors,
pubmed-meshheading:20009911-Treatment Outcome,
pubmed-meshheading:20009911-Vinblastine
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
The role of histology with common first-line regimens for advanced non-small cell lung cancer: a brief report of the retrospective analysis of a three-arm randomized trial.
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|
pubmed:affiliation |
Department of Clinical and Biological Sciences, University of Torino, S. Luigi Hospital, Orbassano, Italy. giorgio.scagliotti@unito.it
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|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase III
|
