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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-3-1
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pubmed:abstractText |
Genome-wide association studies that compare the statistical association between thousands of DNA variations and a human trait have detected 958 loci across 127 different diseases and traits. However, these statistical associations only provide evidence for genomic regions likely to harbor a causal gene(s) and do not directly identify such genes. We combined gene variation and expression data in a human cohort to identify causal genes.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-10611357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-14613964,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-14997420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-15172664,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-16043692,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-16077740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-16255080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-16451707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-16596940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17099226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17167477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17434869,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17463249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17554300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17703236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-17873875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18048838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18251005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18256137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18372903,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18398418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18454136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18855084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-18984658,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-19079260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-19295514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-19587359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-19644074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-19680540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-20393146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-7891719,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-8901667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-9326339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20009087-9545414
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1939-327X
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pubmed:author |
pubmed-author:BlangeroJohnJ,
pubmed-author:CarlessMelanie AMA,
pubmed-author:ColeShelley ASA,
pubmed-author:ComuzzieAnthony GAG,
pubmed-author:CurranJoanne EJE,
pubmed-author:DyerThomas DTD,
pubmed-author:GöringHarald H HHH,
pubmed-author:JohnsonMatthew PMP,
pubmed-author:JowettJeremy B MJB,
pubmed-author:MacCluerJean WJW,
pubmed-author:MosesEric KEK
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pubmed:issnType |
Electronic
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
726-32
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pubmed:dateRevised |
2011-7-25
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pubmed:meshHeading |
pubmed-meshheading:20009087-Chromosomes, Human, Pair 16,
pubmed-meshheading:20009087-Diabetes Mellitus, Type 2,
pubmed-meshheading:20009087-Genetic Linkage,
pubmed-meshheading:20009087-Genetic Variation,
pubmed-meshheading:20009087-Genome-Wide Association Study,
pubmed-meshheading:20009087-Genotype,
pubmed-meshheading:20009087-Humans,
pubmed-meshheading:20009087-Introns,
pubmed-meshheading:20009087-Mexican Americans,
pubmed-meshheading:20009087-Obesity,
pubmed-meshheading:20009087-Polymorphism, Single Nucleotide,
pubmed-meshheading:20009087-Proteins,
pubmed-meshheading:20009087-Retinoblastoma-Like Protein p130
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic variation at the FTO locus influences RBL2 gene expression.
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pubmed:affiliation |
Department of Genomics and Systems Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia. jeremy.jowett@bakeridi.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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