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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0007102,
umls-concept:C0030705,
umls-concept:C0034897,
umls-concept:C0038952,
umls-concept:C0150098,
umls-concept:C0242793,
umls-concept:C0439590,
umls-concept:C0677850,
umls-concept:C0679083,
umls-concept:C0947697,
umls-concept:C1511636,
umls-concept:C1527178,
umls-concept:C1705938
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pubmed:issue |
3
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pubmed:dateCreated |
2010-1-18
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pubmed:abstractText |
We previously validated disease-free survival (DFS) as a surrogate for overall survival (OS) in fluorouracil-based adjuvant colon cancer clinical trials. New therapies have extended survival after recurrence from 1 to approximately 2 years. We examined the possible impact of this improvement on the DFS/OS association.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-10944126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-11006366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-11352309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-14657227,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-15051767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-15175435,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-15175436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-15269313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-16260700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-16849748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-17442997,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-17470858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-17647245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-17704423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-17876008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-17947725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-18421054,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-18467725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-18854571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-19124803,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20008641-19451431
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:AlbertsSteven RSR,
pubmed-author:AndreThierryT,
pubmed-author:BenedettiJacquelineJ,
pubmed-author:BensonAlA,
pubmed-author:BlankeCharles DCD,
pubmed-author:BotBrianB,
pubmed-author:BuyseMarcM,
pubmed-author:DengQiqiQ,
pubmed-author:GoldbergRichard MRM,
pubmed-author:GrotheyAxelA,
pubmed-author:HubbardJoleenJ,
pubmed-author:O'CallaghanChrisC,
pubmed-author:O'ConnellMichael JMJ,
pubmed-author:SargentDanielD,
pubmed-author:ShiQianQ,
pubmed-author:WolmarkNormanN,
pubmed-author:YothersGregG,
pubmed-author:de GramontAimeryA
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
460-5
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pubmed:dateRevised |
2011-7-20
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pubmed:meshHeading |
pubmed-meshheading:20008641-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20008641-Chemotherapy, Adjuvant,
pubmed-meshheading:20008641-Colonic Neoplasms,
pubmed-meshheading:20008641-Disease-Free Survival,
pubmed-meshheading:20008641-Follow-Up Studies,
pubmed-meshheading:20008641-Humans,
pubmed-meshheading:20008641-Neoplasm Recurrence, Local,
pubmed-meshheading:20008641-Survival Analysis,
pubmed-meshheading:20008641-Time Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Association between disease-free survival and overall survival when survival is prolonged after recurrence in patients receiving cytotoxic adjuvant therapy for colon cancer: simulations based on the 20,800 patient ACCENT data set.
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pubmed:affiliation |
Hopital Saint Antoine, Group Hospitalier Pitie-Salpetriere, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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