Linked Life Data

20006445

Source:http://linkedlifedata.com/resource/pubmed/id/20006445

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-2-17
pubmed:abstractText
Inhalation injury is a major cause of morbidity and mortality in thermally injured patients but is difficult to quantify. A number of parameters can be useful evaluating inhalation injury including bronchoscopy, PaO(2)/FiO(2) (P/F) ratio, and carboxyhaemaglobin (COHb) levels. Identification of markers that permit early detection of the degree of damage caused by inhalation injury is important to predict patient survival. In this retrospective study we evaluated the potential of using the P/F ratio, bronchoscopic findings and the COHb level to assess the severity of the inhalation injury in adults. A retrospective review of all patients admitted with inhalation injuries to the intensive care unit (ICU) from January 1995 to December 2002 was conducted and of the 110 patients 105 Casenotes were obtained and investigated. The total burn surface area (TBSA), age and bronchoscopic findings showed a positive correlation with mortality. There was no significant correlation between COHb levels and mortality, but there was a significant correlation between P/F ratio and mortality in adults. Logistic regression indicated that the combination of TBSA, age and P/F ratio was highly predictive of mortality following major burns. This study supports the predictive nature of the P/F ratio in relation to survival in adults. Larger prospective studies using bronchoscopic findings and P/F ratio would give us a better indication as to the value of a scoring system in adults that are admitted with inhalation injuries.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1879-1409
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2009 Elsevier Ltd and ISBI. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
212-6
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Assessing the severity of inhalation injuries in adults.
pubmed:affiliation
Manchester Burns and Plastic Surgery Service, Burns and Wound Research Office, Burn Centre, Acute Block, Wythenshawe Hospital, Manchester, United Kingdom. zhassan99@hotmail.com
pubmed:publicationType
Journal Article, Evaluation Studies