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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-9-29
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pubmed:abstractText |
Rituximab (RTX) has been successfully used in the treatment of several rheumatic diseases with an acceptable safety profile. We present herein a patient with systemic sclerosis (SSc) who exhibited significant improvement of his lung function and skin fibrosis following RTX administration, and review the literature regarding the role of B-cells in SSc and the potential efficacy of RTX in its treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1532-866X
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-36
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pubmed:meshHeading |
pubmed-meshheading:20004954-Adult,
pubmed-meshheading:20004954-Animals,
pubmed-meshheading:20004954-Antibodies, Monoclonal, Murine-Derived,
pubmed-meshheading:20004954-B-Lymphocytes,
pubmed-meshheading:20004954-Disease Models, Animal,
pubmed-meshheading:20004954-Fibrosis,
pubmed-meshheading:20004954-Humans,
pubmed-meshheading:20004954-Immunologic Factors,
pubmed-meshheading:20004954-Lung Diseases, Interstitial,
pubmed-meshheading:20004954-Lymphocyte Activation,
pubmed-meshheading:20004954-Lymphocyte Depletion,
pubmed-meshheading:20004954-Male,
pubmed-meshheading:20004954-Scleroderma, Systemic,
pubmed-meshheading:20004954-Skin
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pubmed:year |
2010
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pubmed:articleTitle |
Is there a role for B-cell depletion as therapy for scleroderma? A case report and review of the literature.
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pubmed:affiliation |
Division of Rheumatology, Department of Internal Medicine, Patras University Hospital, University of Patras Medical School, Patras, Greece. jimdaoussis@hotmail.com
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
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