Linked Life Data

19999660

Source:http://linkedlifedata.com/resource/pubmed/id/19999660

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
21
pubmed:dateCreated
2009-12-15
pubmed:abstractText
The number of persons over 70 years of age with advanced age-related macular degeneration in Finland can be estimated to be approximately 50,000. Milder forms are additionally present in a considerably larger group. Smoking and age are undisputed non-genetic risk factors of age-related macular degeneration. Of the genetic factors, polymorphisms of the complement factor H (CFH) and LOC387715 genes have a strong impact on the risk of developing the disease, whereas alleles of the C3, CFB, and the C1 inhibitor SERPING1 genes of the complement system exhibit only minor effects.
pubmed:language
fin
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0012-7183
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2360-4
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[Identification of susceptibility genes for age-related macular degeneration--a success story of molecular genetics].
pubmed:affiliation
HUS:n silmäsairaala, Haartmaninkatu 2, 00290 Helsinki, ja Helsingin yliopisto, Biomedicum, lääketieteellisen, genetiikan osasto.
pubmed:publicationType
Journal Article, English Abstract