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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-6
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pubmed:abstractText |
Proteasome-mediated protein degradation may contribute to the regulation of intestinal inflammation. At the same time, low-grade inflammation and increased intestinal permeability seem to be involved in the pathophysiology of irritable bowel syndrome (IBS). Thus, we aimed to evaluate proteasome composition and activities in colonic mucosa of IBS patients and its putative pathogenic role.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1572-0241
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pubmed:author |
pubmed-author:AntoniettiMichelM,
pubmed-author:AzizMoutazM,
pubmed-author:Bôle-FeysotChristineC,
pubmed-author:BoukhettalaNabileN,
pubmed-author:CoëffierMoïseM,
pubmed-author:DéchelottePierreP,
pubmed-author:DucrottéPhilippeP,
pubmed-author:GloroRomainR,
pubmed-author:LecleireStéphaneS,
pubmed-author:ReimundJean MarieJM,
pubmed-author:SavoyeGuillaumeG,
pubmed-author:VandaeleNathalieN
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pubmed:issnType |
Electronic
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1181-8
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pubmed:meshHeading |
pubmed-meshheading:19997094-Adult,
pubmed-meshheading:19997094-Analysis of Variance,
pubmed-meshheading:19997094-Biopsy, Needle,
pubmed-meshheading:19997094-Blotting, Western,
pubmed-meshheading:19997094-Case-Control Studies,
pubmed-meshheading:19997094-Cell Membrane Permeability,
pubmed-meshheading:19997094-Crohn Disease,
pubmed-meshheading:19997094-Cytokines,
pubmed-meshheading:19997094-Female,
pubmed-meshheading:19997094-Humans,
pubmed-meshheading:19997094-Immunohistochemistry,
pubmed-meshheading:19997094-Intestinal Mucosa,
pubmed-meshheading:19997094-Irritable Bowel Syndrome,
pubmed-meshheading:19997094-Male,
pubmed-meshheading:19997094-Mast Cells,
pubmed-meshheading:19997094-Membrane Proteins,
pubmed-meshheading:19997094-Middle Aged,
pubmed-meshheading:19997094-Probability,
pubmed-meshheading:19997094-Proteasome Endopeptidase Complex,
pubmed-meshheading:19997094-Reference Values,
pubmed-meshheading:19997094-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19997094-Sensitivity and Specificity,
pubmed-meshheading:19997094-Severity of Illness Index,
pubmed-meshheading:19997094-Statistics, Nonparametric,
pubmed-meshheading:19997094-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Increased proteasome-mediated degradation of occludin in irritable bowel syndrome.
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pubmed:affiliation |
Nutrition Unit, Rouen University Hospital, Rouen, France. moise.coeffier@univ-rouen.fr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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