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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-15
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pubmed:abstractText |
Neutrophils play an essential role in innate immunity and against infection. Mitochondria are organelles that produce energy in the form of adenosine triphosphate (ATP), which is required for maintaining the function and structure of cells and organs. Although local anesthetics (LAs) are widely used in clinical practice, it remains unclear whether LAs such as lidocaine, ropivacaine, and bupivacaine affect neutrophil mitochondrial functions. The aim of this study was to examine whether LAs have any effects on human neutrophil mitochondrial functions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1529-8809
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
401-8
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pubmed:meshHeading |
pubmed-meshheading:19996799-Amides,
pubmed-meshheading:19996799-Anesthetics, Local,
pubmed-meshheading:19996799-Apoptosis,
pubmed-meshheading:19996799-Bupivacaine,
pubmed-meshheading:19996799-Cells, Cultured,
pubmed-meshheading:19996799-Humans,
pubmed-meshheading:19996799-Lidocaine,
pubmed-meshheading:19996799-Mitochondria,
pubmed-meshheading:19996799-Neutrophils,
pubmed-meshheading:19996799-Phagocytosis
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pubmed:year |
2010
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pubmed:articleTitle |
Lidocaine enhances apoptosis and suppresses mitochondrial functions of human neutrophil in vitro.
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pubmed:affiliation |
Department of Anesthesiology, University of Occupational and Environmental Health, Kitakyushu, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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