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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-12-9
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pubmed:abstractText |
In addition to exogenous risk factors, the development of head and neck cancer is based on genetic alterations and individual mutagen sensitivity. DNA damage caused by xenobiotics is not uniformly distributed over the DNA, as certain chromosomes and genes are more likely to be damaged than others. The DNA damaging effect of xenobiotics and the specific sites of chromosomal changes require further investigation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1790-6295
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
247-54
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pubmed:meshHeading |
pubmed-meshheading:19996129-7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide,
pubmed-meshheading:19996129-Adult,
pubmed-meshheading:19996129-Aged,
pubmed-meshheading:19996129-Chromosomes, Human,
pubmed-meshheading:19996129-DNA Damage,
pubmed-meshheading:19996129-Humans,
pubmed-meshheading:19996129-In Situ Hybridization, Fluorescence,
pubmed-meshheading:19996129-Lymphocytes,
pubmed-meshheading:19996129-Male,
pubmed-meshheading:19996129-Middle Aged,
pubmed-meshheading:19996129-Mucous Membrane,
pubmed-meshheading:19996129-Mutagens,
pubmed-meshheading:19996129-Oropharyngeal Neoplasms,
pubmed-meshheading:19996129-Oropharynx
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pubmed:articleTitle |
Chromosomal alterations and mutagen sensitivity in human mucosal cells of the oropharynx and lymphocytes caused by BPDE.
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pubmed:affiliation |
Department of Otorhinolaryngology/Head and Neck Surgery, Grosshadern Clinic, Ludwig Maximilians University, Marchioninistrasse 15, Munich, Germany. maximilian.reiter@med.uni-muenchen.de
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pubmed:publicationType |
Journal Article
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