Germline mutations in BRCA genes are associated with breast and ovarian cancer susceptibility. Because infertility is associated with breast and ovarian cancer risks, we hypothesized that the mutations in the BRCA gene may be associated with low response to fertility treatments.
Association of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between infertility and breast/ovarian cancer risks.
Institute for Fertility Preservation, Department of Obstetrics and Gynecology, New York Medical College-Westchester Medical Center, Valhalla, NY 10595, USA. koktay@fertilitypreservation.org
