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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-12-25
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pubmed:abstractText |
As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-11311121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-16242644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-17135279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-17192785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-17906291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-18509201,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-18658135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-18696092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-19125160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-19184068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-19734902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-19734903,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19995442-6330613
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
pubmed-author:BercianoJoséJ,
pubmed-author:BullidoMaría JMJ,
pubmed-author:FRISCHKORNC SCS,
pubmed-author:FrankAnaA,
pubmed-author:MateoIgnacioI,
pubmed-author:PozuetaAnaA,
pubmed-author:Rodríguez-RodríguezEloyE,
pubmed-author:Sánchez-JuanPascualP,
pubmed-author:SastreIsabelI,
pubmed-author:Vázquez-HigueraJosé LuisJL,
pubmed-author:ValdiviesoFernandoF
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:19995442-Aged,
pubmed-meshheading:19995442-Aged, 80 and over,
pubmed-meshheading:19995442-Alzheimer Disease,
pubmed-meshheading:19995442-Case-Control Studies,
pubmed-meshheading:19995442-Cohort Studies,
pubmed-meshheading:19995442-Female,
pubmed-meshheading:19995442-Genetic Predisposition to Disease,
pubmed-meshheading:19995442-Humans,
pubmed-meshheading:19995442-Male,
pubmed-meshheading:19995442-Middle Aged,
pubmed-meshheading:19995442-Polymorphism, Single Nucleotide,
pubmed-meshheading:19995442-Protein-Serine-Threonine Kinases,
pubmed-meshheading:19995442-Protein-Tyrosine Kinases,
pubmed-meshheading:19995442-Risk Factors,
pubmed-meshheading:19995442-Spain
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pubmed:year |
2009
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pubmed:articleTitle |
DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort.
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pubmed:affiliation |
Neurology Service and CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria, Santander, Spain. josevazquezhiguera@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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