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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1991-4-8
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pubmed:abstractText |
We describe a simple method for characterizing a frequent polymorphism (that substitutes an arginine for a proline) in the coding sequence of the Tp53 gene in patients with colonic cancer and in a control population. We could find no evidence that this polymorphism is associated with a marked predisposition to colorectal cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0340-6717
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
369-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1999338-Base Sequence,
pubmed-meshheading:1999338-Colonic Neoplasms,
pubmed-meshheading:1999338-Gene Frequency,
pubmed-meshheading:1999338-Heterozygote Detection,
pubmed-meshheading:1999338-Humans,
pubmed-meshheading:1999338-Molecular Sequence Data,
pubmed-meshheading:1999338-Oligonucleotide Probes,
pubmed-meshheading:1999338-Polymerase Chain Reaction,
pubmed-meshheading:1999338-Polymorphism, Genetic,
pubmed-meshheading:1999338-Rectal Neoplasms,
pubmed-meshheading:1999338-Reference Values,
pubmed-meshheading:1999338-Tumor Suppressor Protein p53
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pubmed:year |
1991
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pubmed:articleTitle |
Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population.
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pubmed:affiliation |
Laboratoire de Génétique Moléculaire des Tumeurs, Institut Curie, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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