Linked Life Data

1997611

Source:http://linkedlifedata.com/resource/pubmed/id/1997611

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-4-3
pubmed:abstractText
In order to understand the role of Interleukin 1 (IL-1) in human amniotic fluid (AF), the amount of IL-1 in normal human AF at various gestational ages was measured using ELISA. Materials were divided into three groups based on gestational ages. Group 1, less than 22 weeks (n = 16), consisted of AF samples which were collected by amniocentesis. Group 2, greater than or equal to 36 weeks (n = 54), consisted of AF samples collected transvaginally at delivery. Group 3, greater than or equal to 36 weeks (n = 9), transabdominally collected AF samples from elective cesarean section without labor. IL-1 alpha was present in AF of early gestational age in group 1 and appeared to increase with gestational age in group 3. In contrast, IL-1 beta was not detectable in either group 1 or 3. However, the concentration of IL-1 in group 2 was extremely high (IL-1 alpha 201.0 +/- 299.3 pg/ml, IL-1 beta 1,024.1 +/- 1,321.9 pg/ml) when compared to the other groups. Moreover, the IL-1 alpha and IL-1 beta concentrations correlated with those of Prostaglandin E2 and F2 alpha in AF, measured by RIA. These findings suggest that IL-1 has an important role during pregnancy and during labor in particular.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0300-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-8
pubmed:dateRevised
2011-7-29
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[The kinetics of interleukin 1 and prostaglandin concentrations in human amniotic fluid].
pubmed:affiliation
Department of Obstetrics and Gynecology, Sashima Kyodo Hospital, Ibaraki.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't