|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0008838,
umls-concept:C0011209,
umls-concept:C0027651,
umls-concept:C0087111,
umls-concept:C0184511,
umls-concept:C0205314,
umls-concept:C0205373,
umls-concept:C0441994,
umls-concept:C0600688,
umls-concept:C0679622,
umls-concept:C1299000,
umls-concept:C1512956,
umls-concept:C1515655
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2009-12-8
|
|
pubmed:abstractText |
A lymphatically delivered nanoconjugate of cisplatin was evaluated in an orthotopic mouse model of locoregionally metastatic breast cancer (LABC) to determine if it can overcome some of the limitations of standard cisplatin therapy such as high systemic toxicity.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1879-1883
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
198
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
781-6
|
|
pubmed:dateRevised |
2011-9-26
|
|
pubmed:meshHeading |
pubmed-meshheading:19969129-Animals,
pubmed-meshheading:19969129-Antineoplastic Agents,
pubmed-meshheading:19969129-Breast Neoplasms,
pubmed-meshheading:19969129-Cisplatin,
pubmed-meshheading:19969129-Female,
pubmed-meshheading:19969129-Lymphatic System,
pubmed-meshheading:19969129-Mice,
pubmed-meshheading:19969129-Mice, Nude,
pubmed-meshheading:19969129-Nanoparticles,
pubmed-meshheading:19969129-Neoplasm Transplantation,
pubmed-meshheading:19969129-Rats,
pubmed-meshheading:19969129-Rats, Sprague-Dawley
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
A novel intralymphatic nanocarrier delivery system for cisplatin therapy in breast cancer with improved tumor efficacy and lower systemic toxicity in vivo.
|
|
pubmed:affiliation |
Department of Surgery, University of Kansas, Medical Center, Kansas City, KS, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
