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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-5-18
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pubmed:abstractText |
In this pharmacokinetic/pharmacodynamic meta-analysis, we investigated relationships between clinical endpoints and sunitinib exposure in patients with advanced solid tumors, including patients with gastrointestinal stromal tumor (GIST) and metastatic renal cell carcinoma (mRCC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1432-0843
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-71
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pubmed:meshHeading |
pubmed-meshheading:19967539-Adult,
pubmed-meshheading:19967539-Aged,
pubmed-meshheading:19967539-Antineoplastic Agents,
pubmed-meshheading:19967539-Area Under Curve,
pubmed-meshheading:19967539-Blood Pressure,
pubmed-meshheading:19967539-Carcinoma, Renal Cell,
pubmed-meshheading:19967539-Endpoint Determination,
pubmed-meshheading:19967539-Fatigue,
pubmed-meshheading:19967539-Female,
pubmed-meshheading:19967539-Gastrointestinal Stromal Tumors,
pubmed-meshheading:19967539-Humans,
pubmed-meshheading:19967539-Indoles,
pubmed-meshheading:19967539-Kidney Neoplasms,
pubmed-meshheading:19967539-Leukocyte Count,
pubmed-meshheading:19967539-Linear Models,
pubmed-meshheading:19967539-Male,
pubmed-meshheading:19967539-Middle Aged,
pubmed-meshheading:19967539-Neoplasms,
pubmed-meshheading:19967539-Neutrophils,
pubmed-meshheading:19967539-Nonlinear Dynamics,
pubmed-meshheading:19967539-Population,
pubmed-meshheading:19967539-Pyrroles
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pubmed:year |
2010
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pubmed:articleTitle |
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis.
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pubmed:affiliation |
Pfizer Inc., Global Research and Development, 10578 Science Center Drive, CB1, San Diego, CA 92121, USA. brett.houk@pfizer.com
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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