|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2009-12-7
|
|
pubmed:abstractText |
Various caspases have been implicated in the development of secondary damage after spinal cord injury (SCI). Anticaspase therapy that targets only one caspase has been investigated in a variety of in vitro and in vivo studies. This study examined the neuroprotective effects of Q-VD-OPh, a pan-caspase inhibitor, in a rat model of SCI.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1130-1473
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
20
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
533-40; discussion 540
|
|
pubmed:meshHeading |
pubmed-meshheading:19967318-Amino Acid Chloromethyl Ketones,
pubmed-meshheading:19967318-Animals,
pubmed-meshheading:19967318-Apoptosis,
pubmed-meshheading:19967318-Caspases,
pubmed-meshheading:19967318-Hindlimb,
pubmed-meshheading:19967318-In Situ Nick-End Labeling,
pubmed-meshheading:19967318-Male,
pubmed-meshheading:19967318-Quinolines,
pubmed-meshheading:19967318-Rats,
pubmed-meshheading:19967318-Rats, Wistar,
pubmed-meshheading:19967318-Recovery of Function,
pubmed-meshheading:19967318-Spinal Cord,
pubmed-meshheading:19967318-Spinal Cord Injuries
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Q-VD-OPh, a pancaspase inhibitor, reduces trauma-induced apoptosis and improves the recovery of hind-limb function in rats after spinal cord injury.
|
|
pubmed:affiliation |
Department of Neurosurgery, Maltepe University, School of Medicine, Istanbul, Turkey. drahmetcolak@yahoo.com
|
|
pubmed:publicationType |
Journal Article
|
