Linked Life Data

19964731

Source:http://linkedlifedata.com/resource/pubmed/id/19964731

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-12-7
pubmed:abstractText
The aim of this study is to provide a method to track the anatomical alterations of parotid glands during radiation treatment. The method we implemented is based on an intensity-based free-form deformable registration to realign the planning kilo-Voltage CT (kVCT) and the daily Mega-Voltage (MVCT) image sets and on an automatic contour propagation algorithm based on surface construction by triangular mesh. The accuracy of the method was evaluated through visual inspection and comparison with manual contours drawn by expert physicians. The uncertainties of automatic contours were similar to those of manual contours, in terms of parotid volumes and center-of-mass distances. The parotid volumes decreased with a median total loss of 21.7%. We observed an average medial shift of parotid center-of-mass of 3.1 mm from the external part toward the midline. The deformable registration method presented in this work provides an accurate tool for the automatic evaluation of parotid changes occurring during a radiotherapy treatment period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2009
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
94-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
An automatic deformable registration method to evaluate parotid glands shrinkage during radiotherapy treatment in Tomotherapy.
pubmed:affiliation
Bioengineering Department, Politecnico di Milano, Milan, Italy. elena.faggiano@mail.polimi.it
pubmed:publicationType
Journal Article