Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2009-12-3
pubmed:abstractText
CD25, a component of the IL-2 receptor, is important in T cell proliferation, activation induced cell death, as well as the actions of both regulatory (Treg) and effector (Teff) T cells. Recent genome wide association studies have implicated the CD25 locus as an important region for genetic susceptibility to a number of autoimmune disorders, with serum levels of soluble CD25 receptor (sCD25) serving as a potential phenotypic marker for this association. However, the functional impact of CD25 cleavage, as well as the influence of sCD25 on immunoregulatory activities, remain largely unknown and form the basis of this effort.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-10574621, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-10623432, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-11196168, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-11466340, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-11544020, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-12752672, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-14676299, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-14707053, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-15067033, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16106097, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16227984, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16230217, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16467871, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16652285, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16818678, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-16911870, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-17277778, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-17327427, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-17660530, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-17676041, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-17906988, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-18161521, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-18468463, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-19114668, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-19155502, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-2821110, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-2996141, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-3023487, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-3930598, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-7636184, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-9103438, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-9203962, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-9432986, http://linkedlifedata.com/resource/pubmed/commentcorrection/19956753-9755337
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1932-6203
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
e7980
pubmed:dateRevised
2010-9-28
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation.
pubmed:affiliation
Department of Pathology, University of Florida, Gainesville, Florida, United States of America.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural