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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2010-1-28
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pubmed:abstractText |
Amlodipine, a dihydropyridine Ca(2+) channel blocker, inhibits the proliferation of human epidermoid carcinoma A431 cells in vitro and in vivo. This study examined the underlying mechanism of this antiproliferative effect in relation to epidermal growth factor receptor (EGFR) signaling.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
16
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
124-32
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pubmed:meshHeading |
pubmed-meshheading:19951711-Amlodipine,
pubmed-meshheading:19951711-Animals,
pubmed-meshheading:19951711-Antineoplastic Agents,
pubmed-meshheading:19951711-Blotting, Western,
pubmed-meshheading:19951711-Calcium Channel Blockers,
pubmed-meshheading:19951711-Carcinoma, Squamous Cell,
pubmed-meshheading:19951711-Caveolin 1,
pubmed-meshheading:19951711-Cell Culture Techniques,
pubmed-meshheading:19951711-Cell Line, Tumor,
pubmed-meshheading:19951711-Cell Proliferation,
pubmed-meshheading:19951711-Cell Survival,
pubmed-meshheading:19951711-Cholesterol,
pubmed-meshheading:19951711-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:19951711-Humans,
pubmed-meshheading:19951711-Immunoprecipitation,
pubmed-meshheading:19951711-Male,
pubmed-meshheading:19951711-Mice,
pubmed-meshheading:19951711-Mice, Inbred BALB C,
pubmed-meshheading:19951711-Neoplasm Transplantation,
pubmed-meshheading:19951711-Phosphorylation,
pubmed-meshheading:19951711-Receptor, Epidermal Growth Factor,
pubmed-meshheading:19951711-Xenograft Model Antitumor Assays
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pubmed:year |
2010
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pubmed:articleTitle |
Amlodipine, a Ca2+ channel blocker, suppresses phosphorylation of epidermal growth factor receptor in human epidermoid carcinoma A431 cells.
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pubmed:affiliation |
Department of Pharmacology, School of Medicine, Kanazawa Medical University, Daigaku 1-1, Uchinada, Ishikawa 920-0293, Japan. yayuyo@kanazawa-med.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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