| pubmed-article:19949677 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0302592 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C1522449 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0387583 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0475276 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0332293 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:19949677 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:19949677 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:19949677 | pubmed:dateCreated | 2009-12-1 | lld:pubmed |
| pubmed-article:19949677 | pubmed:abstractText | We investigated the correlation between Cyclooxygenase-2 (COX-2) expression and the tumor response in patients with cervical cancer that were treated with curative radiotherapy (RT). Fifty-seven patients with squamous cell carcinoma were treated with concurrent radiochemotherapy (CRCT, n=29) or RT alone (n=28). The response of each patient was evaluated by three serial Magnetic Resonance Imaging examinations: before the start of RT, at four weeks after the start of RT (mid-RT) and at four weeks after the completion of RT (post-RT). Forty-three patients had positive COX-2 expression. The COX-2 negative patients achieved a higher rate of complete response (CR) at mid-RT than did the COX-2 positive patients (28.6% vs. 7.0%, P=0.054), but not at post-RT (64.3% vs. 69.8%). The initial tumor volume was a significant predictor of CR at mid-RT (P=0.003) and post-RT (P=0.004). The multivariate analysis showed that the initial tumor volume (at mid-RT and post-RT) and CRCT (at post-RT) were significant predictors of CR; however, the COX-2 expression was not. In conclusion, the COX-2 expression status has no significant correlation with the tumor response. Further studies on the changes in COX-2 expression levels during RT may be helpful for determination of its role in the tumor response to treatment and patient prognosis. | lld:pubmed |
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| pubmed-article:19949677 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19949677 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19949677 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19949677 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19949677 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19949677 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19949677 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:19949677 | pubmed:issn | 1598-6357 | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:AhnYong... | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:ChoEun YoonEY | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:AhnGeunghwanG | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:HuhSeung... | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:ChoiYoon-LaYL | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:ParkWonW | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:KangMin KyuMK | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:BaeDuk SooDS | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:KimByoung... | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:LimDo... | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:OhDong RyulDR | lld:pubmed |
| pubmed-article:19949677 | pubmed:author | pubmed-author:NamHeerimH | lld:pubmed |
| pubmed-article:19949677 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19949677 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:19949677 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19949677 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19949677 | pubmed:pagination | 1170-6 | lld:pubmed |
| pubmed-article:19949677 | pubmed:dateRevised | 2010-9-28 | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:meshHeading | pubmed-meshheading:19949677... | lld:pubmed |
| pubmed-article:19949677 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19949677 | pubmed:articleTitle | The effect of cyclooxygenase-2 expression on tumor volume response in patients treated with radiotherapy for uterine cervical cancer. | lld:pubmed |
| pubmed-article:19949677 | pubmed:affiliation | Department of Radiation and Oncology, Yeungnam University College of Medicine, Daegu, Korea. | lld:pubmed |
| pubmed-article:19949677 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19949677 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:5743 | entrezgene:pubmed | pubmed-article:19949677 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19949677 | lld:entrezgene |
