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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-15
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pubmed:abstractText |
Angiotensin II has a critical role in the regulation of blood pressure and cell growth and excess activity of the peptide is implicated in the pathogenesis of salt-induced cardiovascular injury. On the other hand, the role of counteracting angiotensin-(1-7) in cardiac structural and functional responses to high salt diet has not been elucidated. Therefore, the present study examined the changes in cardiac angiotensin-(1-7), its forming enzyme angiotensin converting enzyme 2 (ACE2) and receptor mas in response to a high salt diet in spontaneously hypertensive rats (SHR).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin I,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Peptidyl-Dipeptidase A,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled,
http://linkedlifedata.com/resource/pubmed/chemical/Renin,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Chloride, Dietary,
http://linkedlifedata.com/resource/pubmed/chemical/angiotensin I (1-7),
http://linkedlifedata.com/resource/pubmed/chemical/angiotensin converting enzyme 2,
http://linkedlifedata.com/resource/pubmed/chemical/proto-oncogene proteins c-mas-1
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1753-9455
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
17-25
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pubmed:dateRevised |
2011-9-22
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pubmed:meshHeading |
pubmed-meshheading:19946038-Angiotensin I,
pubmed-meshheading:19946038-Angiotensin II,
pubmed-meshheading:19946038-Animals,
pubmed-meshheading:19946038-Blood Pressure,
pubmed-meshheading:19946038-Male,
pubmed-meshheading:19946038-Peptide Fragments,
pubmed-meshheading:19946038-Peptidyl-Dipeptidase A,
pubmed-meshheading:19946038-Proto-Oncogene Proteins,
pubmed-meshheading:19946038-RNA, Messenger,
pubmed-meshheading:19946038-Rats,
pubmed-meshheading:19946038-Rats, Inbred SHR,
pubmed-meshheading:19946038-Receptors, G-Protein-Coupled,
pubmed-meshheading:19946038-Renin,
pubmed-meshheading:19946038-Sodium Chloride, Dietary,
pubmed-meshheading:19946038-Ventricular Dysfunction, Left,
pubmed-meshheading:19946038-Ventricular Remodeling
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pubmed:year |
2010
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pubmed:articleTitle |
Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction.
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pubmed:affiliation |
Hypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. jvaragic@wfubmc.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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