|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0020517,
umls-concept:C0033045,
umls-concept:C0079083,
umls-concept:C0086960,
umls-concept:C0231449,
umls-concept:C0355642,
umls-concept:C0376495,
umls-concept:C0439836,
umls-concept:C0445202,
umls-concept:C0574032,
umls-concept:C0677582,
umls-concept:C1140680,
umls-concept:C1516213,
umls-concept:C1524063
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|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2010-2-15
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|
pubmed:abstractText |
Repeated exposure to carboplatin can lead to hypersensitivity reactions during retreatment with carboplatin. This may prevent its further use in platinum-sensitive ovarian cancer patients. At our institution, an increasing proportion of patients are prophylactically converted to an extended schedule of infusion after 8 cycles of carboplatin. We sought to determine whether an incrementally increasing, extended 3-hour infusion of carboplatin with appropriate premedication was associated with a lower rate of hypersensitivity reactions compared to the standard 30-minute schedule in sequentially treated patients.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1095-6859
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pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
116
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
326-31
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pubmed:meshHeading |
pubmed-meshheading:19944454-Adolescent,
pubmed-meshheading:19944454-Adult,
pubmed-meshheading:19944454-Aged,
pubmed-meshheading:19944454-Aged, 80 and over,
pubmed-meshheading:19944454-Antineoplastic Agents,
pubmed-meshheading:19944454-Carboplatin,
pubmed-meshheading:19944454-Drug Administration Schedule,
pubmed-meshheading:19944454-Drug Hypersensitivity,
pubmed-meshheading:19944454-Fallopian Tube Neoplasms,
pubmed-meshheading:19944454-Female,
pubmed-meshheading:19944454-Humans,
pubmed-meshheading:19944454-Infusions, Intravenous,
pubmed-meshheading:19944454-Middle Aged,
pubmed-meshheading:19944454-Ovarian Neoplasms,
pubmed-meshheading:19944454-Peritoneal Neoplasms,
pubmed-meshheading:19944454-Retrospective Studies,
pubmed-meshheading:19944454-Young Adult
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|
pubmed:year |
2010
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|
pubmed:articleTitle |
The prophylactic conversion to an extended infusion schedule and use of premedication to prevent hypersensitivity reactions in ovarian cancer patients during carboplatin retreatment.
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pubmed:affiliation |
Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
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pubmed:publicationType |
Journal Article
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