Source:http://linkedlifedata.com/resource/pubmed/id/19944200
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-2-22
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pubmed:abstractText |
Implantation of autologous chondrocytes (AC) is a promising option for the treatment of cartilage defects, but problems with cell harvesting, dedifferentiation, or the donor age limit the clinical outcome. Mesenchymal stem cells (MSC) gain much interest because of their simple isolation and multipotential differentiation capacity along with their immunosuppressive properties. The latter might introduce tumor manifestation. The influence of undifferentiated and chondrogenically differentiated MSC or AC on tumor growth and metastasis formation was investigated in a murine melanoma model.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1522-9653
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2009 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
389-96
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pubmed:meshHeading |
pubmed-meshheading:19944200-Animals,
pubmed-meshheading:19944200-Cell Culture Techniques,
pubmed-meshheading:19944200-Cell Differentiation,
pubmed-meshheading:19944200-Chondrocytes,
pubmed-meshheading:19944200-Ear Cartilage,
pubmed-meshheading:19944200-Green Fluorescent Proteins,
pubmed-meshheading:19944200-Luminescent Agents,
pubmed-meshheading:19944200-Melanoma, Experimental,
pubmed-meshheading:19944200-Mesenchymal Stem Cell Transplantation,
pubmed-meshheading:19944200-Mesenchymal Stem Cells,
pubmed-meshheading:19944200-Mice,
pubmed-meshheading:19944200-Neoplasms,
pubmed-meshheading:19944200-Risk Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Tumor risk by tissue engineering: cartilaginous differentiation of mesenchymal stem cells reduces tumor growth.
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pubmed:affiliation |
Institute of Anatomy, Christian Albrechts University, Kiel, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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