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rdf:type |
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lifeskim:mentions |
umls-concept:C0021469,
umls-concept:C0030685,
umls-concept:C0033488,
umls-concept:C0238815,
umls-concept:C0243072,
umls-concept:C0332583,
umls-concept:C0391871,
umls-concept:C0441655,
umls-concept:C0449432,
umls-concept:C0680255,
umls-concept:C1179435,
umls-concept:C1283071,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248,
umls-concept:C1963578
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pubmed:issue |
1
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pubmed:dateCreated |
2010-2-3
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pubmed:abstractText |
The effects of Brazilian green propolis ethanol extract on Cry j1-induced cys-leukotrienes and histamine release from peripheral leukocytes of patients with allergic rhinitis were investigated. One of the key mechanisms for the anti-allergic properties of the extract was revealed to be the suppression of cys-LTs release. Furthermore, a series of propolis components and their phenethyl esters were synthesized and evaluated as inhibitors of cys-LTs release. Artepillin C, baccharin, and kaempferide were the major active components of the ethanol extract. The inhibitory activity of artepillin C phenethyl ester was comparable to that of existing LT synthesis inhibitors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1464-3391
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pubmed:author |
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pubmed:copyrightInfo |
Crown Copyright (c) 2009. Published by Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-7
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pubmed:meshHeading |
pubmed-meshheading:19942440-Animals,
pubmed-meshheading:19942440-Anti-Allergic Agents,
pubmed-meshheading:19942440-Bees,
pubmed-meshheading:19942440-Cell Line, Tumor,
pubmed-meshheading:19942440-Cysteine,
pubmed-meshheading:19942440-Histamine,
pubmed-meshheading:19942440-Humans,
pubmed-meshheading:19942440-Leukocytes,
pubmed-meshheading:19942440-Leukotrienes,
pubmed-meshheading:19942440-Propolis,
pubmed-meshheading:19942440-Rhinitis, Allergic, Seasonal
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pubmed:year |
2010
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pubmed:articleTitle |
Inhibitory activity of Brazilian green propolis components and their derivatives on the release of cys-leukotrienes.
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pubmed:affiliation |
Institute for Bee Products and Health Science, Yamada Apiculture Center, Inc, 194 Ichiba, Kagamino 708-0393, Japan. ht0807@yamada-bee.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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