Source:http://linkedlifedata.com/resource/pubmed/id/19941402
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2009-11-27
|
pubmed:abstractText |
The complete genomic sequencing and characterization of Bovine viral diarrhea virus (BVDV) isolate XJ-04 originated from cattle in China was described. The genomic RNA of the isolate was 12,284 nt long and contained short 5'- untranslated region (UTR), 3'-non-coding regions (NCR), and one open reading frame (ORF) encoding a large polyprotein of 3,895 amino acids with 20 potential N-glycosylation sites. The identity of the isolate XJ-04 with reference strains NADL (BVDV-1) and 890 (BVDV-2) in autoprotease (N(pro)) gene and structural genes (C, E(rns), E1, E2) was analyzed. The percentage of nt and aa identity in analyzed genes indicated that the isolate XJ-04 was closer to the reference strain 890 (BVDV-2) than to NADL (BVDV-1). Phylogenetic analysis revealed that the isolate belonged to BVDV-2a subtype. Furthermore, comparison analysis indicated that the isolate XJ-04 did not contain any genomic insertions that can be directly related to the cytopathic phenotype.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-723X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
53
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
197-202
|
pubmed:meshHeading |
pubmed-meshheading:19941402-5' Untranslated Regions,
pubmed-meshheading:19941402-Animals,
pubmed-meshheading:19941402-Base Sequence,
pubmed-meshheading:19941402-Cattle,
pubmed-meshheading:19941402-Diarrhea Virus 2, Bovine Viral,
pubmed-meshheading:19941402-Genome, Viral,
pubmed-meshheading:19941402-Phylogeny,
pubmed-meshheading:19941402-RNA, Viral
|
pubmed:year |
2009
|
pubmed:articleTitle |
Genomic sequencing and characterization of a Chinese isolate of Bovine viral diarrhea virus 2.
|
pubmed:affiliation |
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, P.R. China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|