Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-11-26
pubmed:abstractText
Dendritic cells (DCs) are key coordinators of the immune response, governing the choice between tolerance and immunity. DCs are professional antigen-presenting cells capable of presenting antigen on MHC molecules and priming CD4 and CD8 T-cell responses. They form a heterogeneous group of cells based on phenotype, location, and function. In this review, murine DCs will be discussed regarding their function with special emphasis on their tissue distribution. Recent findings on DC homeostasis during cancer progression will be presented. Finally, the developmental pathways leading to DC differentiation from their precursors will be summarized.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1940-6029
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
595
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-42
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Review of murine dendritic cells: types, location, and development.
pubmed:affiliation
Division of Molecular Immunology, German Cancer Research Center DKFZ, Heidelberg, Germany.
pubmed:publicationType
Journal Article, Review