Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-11-26
pubmed:abstractText
BACKGROUND: The term juvenile idiopathic arthritis (JIA) describes a clinically heterogeneous group of arthritides. The onset in all subgroups is before 16 years of age, but each group presents with different clinical signs and symptoms. The cause of the disease is unknown, but both genetic and environmental factors are believed to be involved. Management of the disease has greatly improved in recent years due to advances in pharmacologic treatment options (especially with new biologic agents) and the prognosis for patients is better than ever before. However, none of the available drugs has a curative potential. This review provides an overview on the classification and the clinical symptoms of the defined subgroups of JIA as well as pharmacotherapies for it. CONCLUSIONS: Treatment of children with JIA is challenging and complex. Since lengthy therapy might be necessary, a multidisciplinary pediatric rheumatology team is crucial for optimal treatment. Although a cure is unknown at this time, adequate treatment aims to preserve function of the joints as well as normal childhood development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1423-0046
pubmed:author
pubmed:copyrightInfo
Copyright 2009 S. Karger AG, Basel.
pubmed:issnType
Electronic
pubmed:volume
72 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4-12
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Juvenile idiopathic arthritis: classification, clinical presentation and current treatments.
pubmed:affiliation
Department of Pediatric Rheumatology, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany. g.dannecker@klinikum-stuttgart.de
pubmed:publicationType
Journal Article, Review