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pubmed-article:19938104pubmed:abstractTextThe serum of most neuromyelitis optica (NMO) patients contains autoantibodies (NMO-IgGs) directed against the aquaporin-4 (AQP4) water channel located on astrocyte foot processes in the perivessel and subpial areas of the brain. Our objectives were to determine the source of central nervous system (CNS) NMO-IgGs and their role in disease pathogenesis.lld:pubmed
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pubmed-article:19938104pubmed:articleTitleIntrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica.lld:pubmed
pubmed-article:19938104pubmed:affiliationDepartment of Neurology and Ophthalmology, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA. jeffrey.bennett@ucdenver.edulld:pubmed
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