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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-11-30
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pubmed:abstractText |
The serum of most neuromyelitis optica (NMO) patients contains autoantibodies (NMO-IgGs) directed against the aquaporin-4 (AQP4) water channel located on astrocyte foot processes in the perivessel and subpial areas of the brain. Our objectives were to determine the source of central nervous system (CNS) NMO-IgGs and their role in disease pathogenesis.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1531-8249
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pubmed:author |
pubmed-author:AntelJack PJP,
pubmed-author:BautistaKatherineK,
pubmed-author:BennettJeffrey LJL,
pubmed-author:CaseDavidD,
pubmed-author:DupreeCecilyC,
pubmed-author:GildenDonD,
pubmed-author:GlogowskaMagdalenaM,
pubmed-author:HemmerBernhardB,
pubmed-author:KalluriSudhakar ReddySR,
pubmed-author:LamChiwahC,
pubmed-author:NesslerStefanS,
pubmed-author:OwensGregory PGP,
pubmed-author:SaikaliPhilippeP,
pubmed-author:StadelmannChristineC
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pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
617-29
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pubmed:dateRevised |
2011-9-30
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pubmed:meshHeading |
pubmed-meshheading:19938104-Amino Acid Sequence,
pubmed-meshheading:19938104-Animals,
pubmed-meshheading:19938104-Aquaporin 4,
pubmed-meshheading:19938104-Autoantibodies,
pubmed-meshheading:19938104-Biological Markers,
pubmed-meshheading:19938104-Cell Line,
pubmed-meshheading:19938104-Cells, Cultured,
pubmed-meshheading:19938104-Female,
pubmed-meshheading:19938104-Fetus,
pubmed-meshheading:19938104-Humans,
pubmed-meshheading:19938104-Immunoglobulin G,
pubmed-meshheading:19938104-Mice,
pubmed-meshheading:19938104-Middle Aged,
pubmed-meshheading:19938104-Molecular Sequence Data,
pubmed-meshheading:19938104-Neuromyelitis Optica,
pubmed-meshheading:19938104-Rats,
pubmed-meshheading:19938104-Rats, Inbred Lew,
pubmed-meshheading:19938104-Spinal Puncture,
pubmed-meshheading:19938104-Time Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica.
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pubmed:affiliation |
Department of Neurology and Ophthalmology, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA. jeffrey.bennett@ucdenver.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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