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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-11-30
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pubmed:abstractText |
Severe inflammation and astrocyte loss with profound demyelination in spinal cord and optic nerves are typical pathological features of neuromyelitis optica (NMO). A diagnostic hallmark of this disease is the presence of serum autoantibodies against the water channel aquaporin-4 (AQP-4) on astrocytes.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1531-8249
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pubmed:author |
pubmed-author:AdzemovicMilenaM,
pubmed-author:BauerJanJ,
pubmed-author:BergerThomasT,
pubmed-author:BradlMonikaM,
pubmed-author:FujiharaKazuoK,
pubmed-author:ItoyamaYasutoY,
pubmed-author:LassmannHansH,
pubmed-author:MaderSimoneS,
pubmed-author:MisuTatsuroT,
pubmed-author:ReindlMarkusM,
pubmed-author:TakahashiToshiyukiT,
pubmed-author:WatanabeMitsutoshiM
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pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
630-43
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pubmed:meshHeading |
pubmed-meshheading:19937948-Adult,
pubmed-meshheading:19937948-Aged,
pubmed-meshheading:19937948-Animals,
pubmed-meshheading:19937948-Aquaporin 4,
pubmed-meshheading:19937948-Autoantibodies,
pubmed-meshheading:19937948-Cell Line,
pubmed-meshheading:19937948-Female,
pubmed-meshheading:19937948-Humans,
pubmed-meshheading:19937948-Immunoglobulin G,
pubmed-meshheading:19937948-Male,
pubmed-meshheading:19937948-Middle Aged,
pubmed-meshheading:19937948-Neuromyelitis Optica,
pubmed-meshheading:19937948-Rats,
pubmed-meshheading:19937948-Rats, Inbred Lew,
pubmed-meshheading:19937948-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo.
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pubmed:affiliation |
Department of Neuroimmunology, Medical University Vienna, Center for Brain Research, Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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