Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-3-15
pubmed:abstractText
This paper presents a technique for producing uniform dose distributions within the target volume with non-coplanar field arrangements. The method is based upon the principle used for producing homogeneous dose distributions for a pair of fields in two dimensions, namely, that if the isodose distributions for the fields are made parallel to one another, the combined dose distribution will be uniform. For the three-dimensional non-coplanar case, homogeneous target dose distributions are obtained by designing field modifiers which produce a uniform dose distribution on the perpendicular bisector plane for each pair of fields. It is demonstrated that for three non-coplanar fields irradiating a spherical phantom with spherical target volumes, the target dose distribution will be homogeneous for any arbitrary non-coplanar field arrangement. Furthermore, this technique can be extended to any number of fields. Therefore, target dose distributions for non-coplanar plans can be as homogeneous as the coplanar case. An example of the application of the method to the treatment of rectal carcinoma with non-coplanar fields is given. Furthermore, it is demonstrated that the therapeutic ratio is improved over traditional methods for this clinical example.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0360-3016
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-33
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Compensation in three-dimensional non-coplanar treatment planning.
pubmed:affiliation
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021.
pubmed:publicationType
Journal Article