|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2009-11-25
|
|
pubmed:abstractText |
Many models of transplant tolerance have been found to depend on the induction of regulatory T cells (Tregs). Innate immune signals are known to suppress Tregs thereby augmenting immunity by abrogating Treg function. Such signals may also provide a barrier to transplantation tolerance mediated by Tregs. A number of cell surface molecules expressed by Tregs have been found to inhibit Treg activity, the best characterized of which is the glucocorticoid-induced tumor necrosis factor receptor-related (GITR) protein.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Glucocorticoid-Induced...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Nerve Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfrsf18 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf18 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factors
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1534-6080
|
|
pubmed:author |
pubmed-author:CatonAndrew JAJ,
pubmed-author:ChoiYongwonY,
pubmed-author:DengShaopingS,
pubmed-author:DuffPatrick EPE,
pubmed-author:KimJames IJI,
pubmed-author:LeeMajor KMK,
pubmed-author:LeeSeoung-HoonSH,
pubmed-author:LianMoh-MohMM,
pubmed-author:MarkmannJames FJF,
pubmed-author:MooreDaniel JDJ,
pubmed-author:SonawaneSamsher BSB,
pubmed-author:YehHeidiH
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
27
|
|
pubmed:volume |
88
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1169-77
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:19935370-Animals,
pubmed-meshheading:19935370-CD4-Positive T-Lymphocytes,
pubmed-meshheading:19935370-Crosses, Genetic,
pubmed-meshheading:19935370-Epitopes,
pubmed-meshheading:19935370-Flow Cytometry,
pubmed-meshheading:19935370-Glucocorticoid-Induced TNFR-Related Protein,
pubmed-meshheading:19935370-Graft Survival,
pubmed-meshheading:19935370-Humans,
pubmed-meshheading:19935370-Immunosuppression,
pubmed-meshheading:19935370-Inflammation,
pubmed-meshheading:19935370-Lymphocytes,
pubmed-meshheading:19935370-Mice,
pubmed-meshheading:19935370-Mice, Inbred BALB C,
pubmed-meshheading:19935370-Mice, Transgenic,
pubmed-meshheading:19935370-Receptors, Nerve Growth Factor,
pubmed-meshheading:19935370-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:19935370-Signal Transduction,
pubmed-meshheading:19935370-Skin Transplantation,
pubmed-meshheading:19935370-Survival Rate,
pubmed-meshheading:19935370-T-Lymphocytes, Regulatory,
pubmed-meshheading:19935370-Transplantation, Homologous,
pubmed-meshheading:19935370-Tumor Necrosis Factors
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
GITR Blockade Facilitates Treg Mediated Allograft Survival.
|
|
pubmed:affiliation |
Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
