rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-11-20
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pubmed:abstractText |
Two types of tumor hypoxia most likely exist in human cancers: Chronic hypoxia due to the paucity of blood capillaries and acute hypoxia due to temporary shutdoWn of microvasculatures or fluctuation in the red cell flux. In a recent hypoxia imaging study using 18F-FMISO PET, the authors observed variation in tracer uptake in two sequential images and hypothesized that variation in acute hypoxia may be the cause. In this study, they develop an iterative optimization method to delineate chronic and acute hypoxia based on the 18F-FMISO PET serial images.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0094-2405
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
36
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4400-8
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pubmed:dateRevised |
2010-10-4
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pubmed:meshHeading |
pubmed-meshheading:19928070-Acute Disease,
pubmed-meshheading:19928070-Algorithms,
pubmed-meshheading:19928070-Cell Hypoxia,
pubmed-meshheading:19928070-Chronic Disease,
pubmed-meshheading:19928070-Computer Simulation,
pubmed-meshheading:19928070-Head and Neck Neoplasms,
pubmed-meshheading:19928070-Humans,
pubmed-meshheading:19928070-Image Enhancement,
pubmed-meshheading:19928070-Image Interpretation, Computer-Assisted,
pubmed-meshheading:19928070-Male,
pubmed-meshheading:19928070-Misonidazole,
pubmed-meshheading:19928070-Models, Biological,
pubmed-meshheading:19928070-Oxygen,
pubmed-meshheading:19928070-Radiopharmaceuticals,
pubmed-meshheading:19928070-Reproducibility of Results,
pubmed-meshheading:19928070-Sensitivity and Specificity,
pubmed-meshheading:19928070-Subtraction Technique
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pubmed:year |
2009
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pubmed:articleTitle |
Modeling acute and chronic hypoxia using serial images of 18F-FMISO PET.
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pubmed:affiliation |
Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1250 1st Avenue, New York, New York 10065, USA.
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pubmed:publicationType |
Journal Article
|