rdf:type |
|
lifeskim:mentions |
umls-concept:C0006114,
umls-concept:C0010286,
umls-concept:C0011854,
umls-concept:C0067684,
umls-concept:C0205329,
umls-concept:C0205341,
umls-concept:C0205355,
umls-concept:C0220982,
umls-concept:C0270611,
umls-concept:C0332120,
umls-concept:C0332189,
umls-concept:C0332307,
umls-concept:C0456603,
umls-concept:C0547047,
umls-concept:C1521910
|
pubmed:issue |
4
|
pubmed:dateCreated |
2010-4-13
|
pubmed:abstractText |
Recent data suggest that DKA may contribute to cognitive impairment in children with type 1 DM. We measured the NAA/Cr ratio in a teenager during and following 2 separate episodes of DKA without clinically apparent cerebral edema. The NAA/Cr ratio decreased during DKA and improved following recovery. However, the NAA/Cr value was lower after the second episode of DKA (1.76) than after the first (1.97). These findings provide support for the hypothesis that neuronal injury may result from DKA.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1936-959X
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
780-1
|
pubmed:meshHeading |
pubmed-meshheading:19926705-Adolescent,
pubmed-meshheading:19926705-Aspartic Acid,
pubmed-meshheading:19926705-Basal Ganglia,
pubmed-meshheading:19926705-Blood Glucose,
pubmed-meshheading:19926705-Brain,
pubmed-meshheading:19926705-Brain Damage, Chronic,
pubmed-meshheading:19926705-Brain Edema,
pubmed-meshheading:19926705-Creatine,
pubmed-meshheading:19926705-Diabetes Mellitus, Type 1,
pubmed-meshheading:19926705-Diabetic Ketoacidosis,
pubmed-meshheading:19926705-Dominance, Cerebral,
pubmed-meshheading:19926705-Humans,
pubmed-meshheading:19926705-Magnetic Resonance Spectroscopy,
pubmed-meshheading:19926705-Male
|
pubmed:year |
2010
|
pubmed:articleTitle |
Progressive decrease in N-acetylaspartate/Creatine ratio in a teenager with type 1 diabetes and repeated episodes of ketoacidosis without clinically apparent cerebral edema: Evidence for permanent brain injury.
|
pubmed:affiliation |
Departments of Radiology, University of California, Davis School of Medicine and UC Davis Children's Hospital, Sacramento, USA. sandra.gorges@ucdmc.ucdavis.edu
|
pubmed:publicationType |
Journal Article,
Case Reports
|