19924513

Source:http://linkedlifedata.com/resource/pubmed/id/19924513

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021368, umls-concept:C0034693, umls-concept:C0034721, umls-concept:C0163159, umls-concept:C0205225, umls-concept:C0206116
pubmed:issue	6
pubmed:dateCreated	2010-5-13
pubmed:abstractText	The aim of this study was to investigate the signal transduction pathways involved in sulforaphane (SF) mediated inhibition of the inflammatory response to lipopolysaccharide (LPS). Additionally, we investigated the effects of SF and LPS on the activity of Nrf2.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9508160
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents, http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP..., http://linkedlifedata.com/resource/pubmed/chemical/JNK Mitogen-Activated Protein..., http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Luciferases, http://linkedlifedata.com/resource/pubmed/chemical/NF-E2-Related Factor 2, http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B, http://linkedlifedata.com/resource/pubmed/chemical/Nfe2l2 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Nitrites, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Thiocyanates, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-1, http://linkedlifedata.com/resource/pubmed/chemical/sulforafan
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1420-908X
pubmed:author	pubmed-author:BrandenburgLars-OveLO, pubmed-author:KippMarkusM, pubmed-author:LuciusRalphR, pubmed-author:PufeThomasT, pubmed-author:WruckChristoph JCJ
pubmed:issnType	Electronic
pubmed:volume	59
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	443-50
pubmed:meshHeading	pubmed-meshheading:19924513-Animals, pubmed-meshheading:19924513-Anti-Inflammatory Agents, pubmed-meshheading:19924513-Blotting, Western, pubmed-meshheading:19924513-Cells, Cultured, pubmed-meshheading:19924513-Cytokines, pubmed-meshheading:19924513-Extracellular Signal-Regulated MAP Kinases, pubmed-meshheading:19924513-Inflammation, pubmed-meshheading:19924513-JNK Mitogen-Activated Protein Kinases, pubmed-meshheading:19924513-Lipopolysaccharides, pubmed-meshheading:19924513-Luciferases, pubmed-meshheading:19924513-Microglia, pubmed-meshheading:19924513-NF-E2-Related Factor 2, pubmed-meshheading:19924513-NF-kappa B, pubmed-meshheading:19924513-Nitrites, pubmed-meshheading:19924513-Phosphorylation, pubmed-meshheading:19924513-RNA, Messenger, pubmed-meshheading:19924513-Rats, pubmed-meshheading:19924513-Rats, Wistar, pubmed-meshheading:19924513-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:19924513-Signal Transduction, pubmed-meshheading:19924513-Thiocyanates, pubmed-meshheading:19924513-Transcription Factor AP-1
pubmed:year	2010
pubmed:articleTitle	Sulforaphane suppresses LPS-induced inflammation in primary rat microglia.
pubmed:affiliation	Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany. lbrandenburg@ukaachen.de
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't