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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001455,
umls-concept:C0007634,
umls-concept:C0017687,
umls-concept:C0018866,
umls-concept:C0044602,
umls-concept:C0285761,
umls-concept:C1150481,
umls-concept:C1171346,
umls-concept:C1368105,
umls-concept:C1451005,
umls-concept:C1704259,
umls-concept:C1705325,
umls-concept:C1705987,
umls-concept:C1820288
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pubmed:issue |
3
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|
pubmed:dateCreated |
2010-3-25
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|
pubmed:abstractText |
That glucagonlike peptide-1 (GLP-1) induces differentiation of primate embryonic stem (ES) cells into insulin-producing cells has been reported by several groups and also confirmed with our observations.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
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pubmed:issn |
1536-4828
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
315-22
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19924023-Cell Differentiation,
pubmed-meshheading:19924023-Cyclic AMP,
pubmed-meshheading:19924023-Down-Regulation,
pubmed-meshheading:19924023-Embryonic Stem Cells,
pubmed-meshheading:19924023-Glucagon-Like Peptide 1,
pubmed-meshheading:19924023-Hedgehog Proteins,
pubmed-meshheading:19924023-Humans,
pubmed-meshheading:19924023-Insulin-Secreting Cells,
pubmed-meshheading:19924023-Octamer Transcription Factor-3,
pubmed-meshheading:19924023-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:19924023-RNA-Directed DNA Polymerase,
pubmed-meshheading:19924023-Telomerase,
pubmed-meshheading:19924023-Transcription Factor AP-1,
pubmed-meshheading:19924023-Transcription Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Glucagon like peptide-1-directed human embryonic stem cells differentiation into insulin-producing cells via hedgehog, cAMP, and PI3K pathways.
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pubmed:affiliation |
UCLA Center of Excellence in Pancreatic Disease, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024-7073, USA. huihongx@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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