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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2 ( Pt 1)
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pubmed:dateCreated |
1991-3-14
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pubmed:abstractText |
We describe 5 patients with a relapsing encephalopathy in association with Hashimoto's disease and high titers of anti-thyroid antibodies. The presentation is usually with a subacute onset of confusion, alteration in conscious level, and focal or generalized seizures. The relapsing course, association with myoclonus or tremulousness, and episodes of stroke-like deterioration are characteristic features. The long-term prognosis is favorable with steroid therapy, though additional immunosuppressive therapy may be required. Neurologic investigation typically shows a diffusely abnormal EEG, high CSF protein level without pleocytosis, and normal brain CT and cerebral angiogram. Isotope brain scan may show patchy abnormal uptake. Hashimoto's encephalopathy should be recognized as a definite neurologic entity and added to the list of CNS complications of thyroid disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
228-33
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:1992366-Adolescent,
pubmed-meshheading:1992366-Autoantibodies,
pubmed-meshheading:1992366-Brain Diseases,
pubmed-meshheading:1992366-Electroencephalography,
pubmed-meshheading:1992366-Female,
pubmed-meshheading:1992366-Humans,
pubmed-meshheading:1992366-Middle Aged,
pubmed-meshheading:1992366-Recurrence,
pubmed-meshheading:1992366-Steroids,
pubmed-meshheading:1992366-Thyroid Gland,
pubmed-meshheading:1992366-Thyroiditis, Autoimmune,
pubmed-meshheading:1992366-Tomography, X-Ray Computed
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pubmed:year |
1991
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pubmed:articleTitle |
Hashimoto's encephalopathy: a steroid-responsive disorder associated with high anti-thyroid antibody titers--report of 5 cases.
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pubmed:affiliation |
Department of Neurology, University of Newcastle upon Tyne, UK.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
|